The effect of the drug
Winstrol’s primary mechanism of action is by binding to cellular androgen receptors. Additionally, Winstrol is credited with having a mild anti-progesterone property, although this has not been fully studied.
There is one more important feature. As a derivative of DHT, Winstrol has the advantage that all drugs in this family have: it is unable to interact with an enzyme called aromatase, which converts androgens into estrogens. Thus, Winstrol is free from estrogen-related side effects, such as fluid retention and the associated risk of high blood pressure.
As a modified form of DHT, Winstrol is not subject to the action of 5-alpha-reductase, the enzyme responsible for converting testosterone into dihydrotestosterone. In addition, the transformations performed prolonged the half-life of the drug (about a day for the injected form and 9 hours for the oral form).
It is important to note that the injectable and oral forms of Winstrol share the same chemical structure. The vast majority of other anabolic steroids are regulated differently – oral drugs are alkylated, while injectables do not have a methyl group but have esters added to them to increase half-life.
This property of Winstrol raises certain concerns due to increased hepatotoxicity – since both forms are alkylated, they have a similar negative effect on the liver. However, the injectable drug is still less of a burden because the first passage through the liver does not occur when ingested. However, this feature must be taken into account when determining the duration of the study.
Stanozolol Side Effects:
An increase in blood pressure.
increase in LDL.
Increase in the number of red blood cells and hemoglobin.
Reduces the amount of synovial fluid and interstitial fluid, which increases the likelihood of injury to the articular-ligament apparatus.